The neuronal cytoskeleton in acute brain injury

Br J Neurosurg. 1998 Aug;12(4):313-7. doi: 10.1080/02688699844808.

Abstract

The microtubules, neurofilaments and microfilaments of the neuronal cytoskeleton are essential for the normal functioning of the neurone. Recent studies have shown that disruption of the cytoskeleton may represent a final pathway in many types of neuronal cell injury with both the somato-dendritic and axonal cytoskeleton being affected. This review discusses the current evidence on the role of the neuronal cytoskeleton in the pathogenesis of traumatic brain damage.

Publication types

  • Review

MeSH terms

  • Brain Injuries / metabolism
  • Brain Injuries / pathology*
  • Cytoskeleton / metabolism
  • Cytoskeleton / pathology*
  • Forecasting
  • Hippocampus / metabolism
  • Humans
  • Microtubule-Associated Proteins / metabolism
  • Neurons / metabolism
  • Neurons / pathology*

Substances

  • Microtubule-Associated Proteins