The authors report the case of a 47-year-old depressive woman treated with citalopram 20 mg day-1 for 3 months who presented a marked sinus bradycardia (34 beats/min) 11 days after the citalopram dose was increased to 40 mg day-1. The bradycardia was clinically asymptomatic and disappeared within 24 h after citalopram was stopped. Citalopram blood levels were in the usual therapeutic range.
Copyright 1999 The Italian Pharmacological Society.