Aim: To determine the incidence of Parkinson's disease in Navarra, province of Spain.
Patients and methods: All patients diagnosed as suffering from Parkinson's disease or related disorders for the neurologists of the region during the period 1994-1995 inclusive were referred to the study. EUROPARKINSON protocol and an epidemiological questionnaire were employed for the assessment.
Results: A total of 132 cases of idiopathic (86) and secondary (45) Parkinson's disease were diagnosed during that period. Among men the age adjusted incidence of idiopathic Parkinson's disease was 10.06 x 10(5), while for women it was 4.92 x 10(5). Total adjusted incidence was 7.36 x 10(5). The average age at onset was 67.5 years in men and 72.6 years in women (p < or = 0.007). Men showed an age adjusted incidence of secondary parkinsonism of 3.34 x 10(5) and women of 4.23 x 10(5). Age at onset was earlier in women than in men (71.2 and 74.8 years, respectively).
Conclusions: The incidence of idiopathic Parkinson's disease in Navarra is higher in men than in women, also supported for an earlier age at onset in men. The epidemiological pattern of secondary Parkinson's disease differs from that of the idiopathic disease.