Comparison of mechanical and transepithelial debridement during photorefractive keratectomy

Ophthalmology. 1999 Mar;106(3):483-9. doi: 10.1016/S0161-6420(99)90135-5.


Objective: Comparison of clinical results from mechanical and transepithelial debridement during photorefractive keratectomy.

Design: Randomized, prospective study.

Participants: Two hundred seventy-eight eyes in 173 patients between November 1995 and June 1997.

Intervention: Photorefractive keratectomy treatments with a Summit Omnimed excimer laser (6-mm). Clinical results were measured at 1, 3, and 6 months.

Main outcomes measures: Uncorrected visual acuity (UCVA), best spectacle-corrected visual acuity (BCVA), mean spherical equivalent (MSE), astigmatism, corneal haze, and subjective vision (day, night, glare, and halo).

Results: At all postoperative intervals, no significant difference was present between mean values of MSE, haze, or any subjective parameters. For mean UCVA, BCVA, and astigmatism values, a significant difference (P < 0.05) was present only at 6 months. At all postoperative intervals, mechanical values tended to be superior to transepithelial valves.

Conclusion: Clinical results were not statistically different between the two techniques; however, the mechanical technique tended to have superior values for almost all tested parameters.

Publication types

  • Clinical Trial
  • Comparative Study
  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Debridement / methods*
  • Epithelium, Corneal / surgery*
  • Female
  • Glare
  • Humans
  • Lasers, Excimer
  • Male
  • Middle Aged
  • Myopia / surgery*
  • Photorefractive Keratectomy*
  • Postoperative Complications
  • Prospective Studies
  • Visual Acuity