Expression of mouse semaphorin H mRNA in the inner ear of mouse fetuses

Neurosci Lett. 1999 Feb 12;261(1-2):127-9. doi: 10.1016/s0304-3940(98)00988-4.


Semaphorins constitute a large family of secreted and cell-surfaced proteins that appear to function as chemorepellents to guide axons. We examined the expression pattern of M-semaH mRNA in the inner ear of mouse fetuses by in situ hybridization histochemistry. M-semaH mRNA expression was high in the endolymphatic sac involved in endolymph homeostasis. It was also high in the semicircular ducts except for the crista ampullaris, whereas no expression was detected in the epithelium of cochlear ducts.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Axons / chemistry
  • Axons / physiology
  • Cytoskeletal Proteins
  • Gene Expression Regulation, Developmental
  • Glycoproteins / genetics*
  • In Situ Hybridization
  • Membrane Proteins*
  • Mice
  • Neurons, Afferent / chemistry
  • Neurons, Afferent / physiology
  • RNA, Messenger / analysis
  • Semaphorins
  • Vestibule, Labyrinth / chemistry*
  • Vestibule, Labyrinth / embryology*
  • Vestibule, Labyrinth / physiology


  • Cytoskeletal Proteins
  • Glycoproteins
  • Membrane Proteins
  • RNA, Messenger
  • Sema3e protein, mouse
  • Semaphorins