Atrial and venous thrombosis secondary to septic arthritis of the sacroiliac joint in a child with hereditary protein C deficiency

J Pediatr Orthop. Mar-Apr 1999;19(2):156-60. doi: 10.1097/00004694-199903000-00004.


Septic arthritis and osteomyelitis in children is seldom accompanied by calf vein thrombosis and rarely by atrial thrombosis. We report the case of an 11-year, 5-month-old boy with septic arthritis and osteomyelitis of the sacroiliac region who developed deep venous thrombosis, in addition to life-threatening right atrial thrombosis. After an intensive hematologic investigation, a hereditary protein C deficiency was revealed. The association of venous thrombosis with septic arthritis or osteomyelitis should raise the possibility of the presence of protein C deficiency.

Publication types

  • Case Reports

MeSH terms

  • Arthritis, Infectious / complications*
  • Child
  • Coronary Thrombosis / complications*
  • Femoral Vein
  • Heart Atria
  • Humans
  • Male
  • Popliteal Vein
  • Protein C Deficiency / complications*
  • Retrospective Studies
  • Sacroiliac Joint*
  • Venous Thrombosis / complications*