Bone mineral density and depression: a community study in women

J Psychosom Res. 1999 Jan;46(1):29-35. doi: 10.1016/s0022-3999(98)00064-6.


In a community sample of 102 Portuguese white women we evaluated the relationship between osteoporosis and indexes of psychopathology and well-being. Depressive symptoms were assessed by the Beck Depression Inventory (BDI), psychopathology by the Hopkins Symptom Checklist-90 Revised (SCL-90-R), and quality of life using the Psychological General Well-Being Index. A questionnaire comprising social, demographic, clinical, and behavioral characteristics was also used. The sample prevalence of osteoporosis was 47.1%. Women with osteoporosis presented significantly higher scores on the total BDI (16+/-9 vs. 13+/-10, p=0.045) and lower scores in the hostility (0.8+/-0.6 vs. 1.2+/-0.7, p=0.012) and phobic anxiety (1.1+/-0.8 vs. 1.5+/-0.9, p=0.041) subscales of the SCL-90-R. No differences were found regarding mean general well-being scores (62+/-17 vs. 64+/-19, p=0.665). This study showed that women with osteoporosis have significantly higher levels of depressive symptoms and a corresponding higher prevalence of depression, independent of other factors strongly associated with osteoporosis, such as age or body mass index.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Bone Density / physiology*
  • Community Networks
  • Depressive Disorder / diagnosis
  • Depressive Disorder / psychology*
  • Female
  • Hostility
  • Humans
  • Middle Aged
  • Osteoporosis / diagnosis*
  • Osteoporosis / psychology
  • Phobic Disorders / diagnosis
  • Phobic Disorders / psychology
  • Portugal
  • Quality of Life
  • Surveys and Questionnaires