Transient left ventricular dysfunction in childhood sickle cell disease

Pediatr Cardiol. May-Jun 1999;20(3):221-3. doi: 10.1007/s002469900447.


For unclear reasons, myocardial infarction is rare in childhood sickle cell disease, whereas lung, bone, and brain infarcts are more common. During vasoocclusive crisis and infection, acute myocardial ischemia and chronic volume overload from anemia may result in myocardial dysfunction. We report a child who had reversible cardiac dysfunction that mimicked myocardial infarction.

Publication types

  • Case Reports

MeSH terms

  • Child
  • Diagnosis, Differential
  • Echocardiography
  • Electrocardiography
  • Exercise Test
  • Follow-Up Studies
  • Heart Rate
  • Hemoglobin SC Disease / complications*
  • Hemoglobin SC Disease / diagnosis
  • Humans
  • Male
  • Myocardial Contraction
  • Myocardial Infarction / diagnosis
  • Ventricular Dysfunction, Left / diagnosis
  • Ventricular Dysfunction, Left / etiology*