A new way of removing silicone oil from the surface of silicone intraocular lenses

Graefes Arch Clin Exp Ophthalmol. 1999 Mar;237(3):201-6. doi: 10.1007/s004170050219.


Purpose: This study was performed to ascertain the efficacy of Perfluorhexyl-octan, C14F13H17 (F6H8), in dissolving silicone oil from the surface of silicone intraocular lenses. So far F6H8 is the only solvent of silicone oil that is tolerated by intraocular tissues.

Materials and methods: Intraocular silicone lenses (Domilens) were examined after application of small droplets of silicone oil of two different viscosities (AdatoSIL-OL 1000 and 5000) followed by rinsing with F6H8. To allow distinction between silicone oil and F6H8 the silicone oil was stained. Microscopic examination was carried out under video control.

Results: One hundred microliters of AdatoSIL-OL 1000 could be easily removed with about 800 microl of F6H8; 50 microl of AdatoSIL-OL 5000 also disappeared after 800 microl of F6H8. A larger drop of the latter oil could not be removed even after application of 2 ml of F6H8.

Conclusion: Silicone oil 1000 can be easily dissolved by F6H8, whereas silicone oil 5000 is more difficult to remove because of its higher viscosity.

Publication types

  • Comparative Study

MeSH terms

  • Equipment Contamination / prevention & control*
  • Fluorocarbons / pharmacology*
  • Humans
  • Lenses, Intraocular*
  • Microscopy, Atomic Force
  • Silicone Oils / chemistry*
  • Surface Properties
  • Video Recording
  • Viscosity


  • Fluorocarbons
  • Silicone Oils
  • perfluorohexyl-octan