Optic atrophy and chronic acquired polyneuropathy

J Neuroophthalmol. 1999 Mar;19(1):67-9. doi: 10.1097/00041327-199903000-00022.


Chronic inflammatory demyelinating polyneuropathy (CIDP) is a chronic, multifocal disorder usually defined as limited to the peripheral nervous system. Multifocal motor neuropathy, an acquired demyelinating neuropathy with conduction block affecting motor neurons only, may be a pathogenically distinct syndrome or a predominantly motor variant of chronic inflammatory demyelinating polyneuropathy. Central nervous system demyelination including optic neuropathy has been reported uncommonly previously in these entities. We report two cases and review the literature on the possible association of optic neuropathy and chronic acquired polyneuropathy.

Publication types

  • Case Reports

MeSH terms

  • Chronic Disease
  • Demyelinating Diseases / complications
  • Electromyography
  • Female
  • Hereditary Sensory and Motor Neuropathy / complications*
  • Humans
  • Magnetic Resonance Imaging
  • Middle Aged
  • Optic Atrophy / complications*
  • Visual Acuity