During the last year, ophthalmology has continued to benefit from an ordered approach to unraveling the pathophysiology and treatment of retinopathy of prematurity. Over the last year, new incidence and treatment information from the Cryotherapy for Retinopathy of Prematurity Study has been presented. The use of the indirect laser to treat retinopathy of prematurity has been introduced. Scleral buckling and vitrectomy continue to define themselves in the management of advanced retinopathy of prematurity. Oxygen continues to be deemphasized as a solitary causative agent in retinopathy of prematurity, and other biochemical agents are being explored as playing a role in the pathogenesis and treatment.