Theoretical prediction of mutagenicity and carcinogenicity of chemical substances

Cancer Biochem Biophys. 1976;1(6):295-8.

Abstract

The pseudopotential with respect to free electrons has been calculated for a series of chemical substances. These potentials are different for carcinogenic, mutagenic-carcinogenic, and mutagenic substances thus allowing the theoretical prediction of their biological activity. The reaction mechanism is discussed on the basis of the interaction potential.

MeSH terms

  • Amino Acids
  • Carcinogens*
  • Chemical Phenomena
  • Chemistry, Physical
  • Models, Biological
  • Mutagens*
  • Purines
  • Pyrimidines

Substances

  • Amino Acids
  • Carcinogens
  • Mutagens
  • Purines
  • Pyrimidines