Abstract
The isolated perfused lung is a valuable tool for studying many lung functions. The kinds of information one can obtain from the isolated perfused lung are illustrated by examples from our studies on the uptake, accumulation, and metabolism of endogenous and exogenous chemicals.
MeSH terms
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Animals
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Dextrans / metabolism
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Imipramine / metabolism
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In Vitro Techniques
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Kinetics
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Lung / metabolism*
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Methadone / metabolism
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Methods
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Perfusion
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Polyethylene Glycols / metabolism
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Prostaglandins / metabolism
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Rabbits
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Time Factors
Substances
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Dextrans
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Prostaglandins
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Polyethylene Glycols
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Imipramine
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Methadone