Fluorescent probes for living cells

Histochem J. 1998 Mar;30(3):123-40. doi: 10.1023/a:1003287101868.


The functional characteristics of fluorescent probes used for imaging and measuring dynamic processes in living cells are reviewed. Initial consideration is given to general design requirements for delivery, targeting, detectability and fluorescence readout, and current technologies for attaining them. Discussion then proceeds to the more application-specific properties of intracellular ion indicators, membrane potential sensors, probes for proteins and lipids, and cell viability markers.

Publication types

  • Review

MeSH terms

  • Animals
  • Cell Physiological Phenomena*
  • Cytological Techniques*
  • Cytoplasm / metabolism
  • Drug Design
  • Fluoresceins* / chemistry
  • Fluoresceins* / metabolism
  • Fluorescent Dyes* / chemistry
  • Fluorescent Dyes* / metabolism
  • Humans
  • Structure-Activity Relationship


  • Fluoresceins
  • Fluorescent Dyes