Analgesic, antiinflammatory and hypoglycaemic activities of Sida cordifolia

Phytother Res. 1999 Feb;13(1):75-7. doi: 10.1002/(SICI)1099-1573(199902)13:1<75::AID-PTR387>3.0.CO;2-F.

Abstract

Sida cordifolia extracts of the aerial and root parts showed good analgesic, antiinflammatory and hypoglycaemic activities. The ethyl acetate (EA) extract of root (SCR-E) showed comparable antiinflammatory activity with indomethacin and possessed significantly higher activity when compared with that of the methanol extract of the root part (SCR-M). The ethyl acetate extract of both root and aerial parts of Sida cordifolia (SCR-E and SCA-E) showed very good central and peripheral analgesic activities at a dose of 600 mg/kg. The methanol extract of root (SCR-M) was found to possess significant hypoglycaemic activity.

MeSH terms

  • Animals
  • Anti-Inflammatory Agents, Non-Steroidal / pharmacology*
  • Blood Glucose / metabolism
  • Carrageenan
  • Edema / chemically induced
  • Edema / drug therapy
  • Hypoglycemic Agents / pharmacology*
  • India
  • Male
  • Mice
  • Pain Measurement / drug effects
  • Plant Extracts / pharmacology*
  • Plant Leaves / chemistry
  • Plant Roots / chemistry
  • Plant Stems / chemistry
  • Plants, Medicinal / chemistry*
  • Rats
  • Rats, Wistar
  • Reaction Time / drug effects

Substances

  • Anti-Inflammatory Agents, Non-Steroidal
  • Blood Glucose
  • Hypoglycemic Agents
  • Plant Extracts
  • Carrageenan