Atm haploinsufficiency results in increased sensitivity to sublethal doses of ionizing radiation in mice

Nat Genet. 1999 Apr;21(4):359-60. doi: 10.1038/7684.
No abstract available

Publication types

  • Letter

MeSH terms

  • Aging / genetics
  • Aging / radiation effects
  • Animals
  • Ataxia Telangiectasia Mutated Proteins
  • Cell Cycle Proteins
  • DNA-Binding Proteins
  • Dose-Response Relationship, Radiation
  • Hair Color / radiation effects
  • Haplotypes
  • Longevity / genetics
  • Longevity / radiation effects
  • Mice
  • Mice, Mutant Strains / genetics*
  • Neoplasms, Radiation-Induced / genetics
  • Neoplasms, Radiation-Induced / pathology
  • Protein-Serine-Threonine Kinases*
  • Proteins / genetics*
  • Proteins / radiation effects
  • Radiation Tolerance / genetics*
  • Survival Rate
  • Tumor Suppressor Proteins

Substances

  • Cell Cycle Proteins
  • DNA-Binding Proteins
  • Proteins
  • Tumor Suppressor Proteins
  • Ataxia Telangiectasia Mutated Proteins
  • Atm protein, mouse
  • Protein-Serine-Threonine Kinases