Quadruple cancer including bilateral breasts, Vater's papilla, and urinary bladder: report of a case

Surg Today. 1999;29(3):276-9. doi: 10.1007/BF02483022.


We herein report a rare case of quadruple carcinoma with heterochronous bilateral breast cancer, cancer of Vater's papilla, and cancer of the urinary bladder, which were all curatively resected. A 62-year-old woman previously underwent right and left modified radical mastectomies heterochronously. Recently, a dilatation of the lower bile duct, diagnosed as cancer of Vater's papilla, was resected by a pancreatoduodenectomy. Hematuria during surgery led to the discovery of a solid bladder tumor. The tumor was resected by a transurethral resection. The histopathologic findings differed for all four lesions. The patient had an uneventful postoperative course and to date has shown no recurrence.

Publication types

  • Case Reports

MeSH terms

  • Adenocarcinoma / pathology*
  • Adenocarcinoma / surgery
  • Adenocarcinoma, Papillary / pathology*
  • Adenocarcinoma, Papillary / surgery
  • Ampulla of Vater*
  • Breast Neoplasms / pathology*
  • Breast Neoplasms / surgery
  • Carcinoma, Papillary / pathology*
  • Carcinoma, Papillary / surgery
  • Carcinoma, Transitional Cell / pathology*
  • Carcinoma, Transitional Cell / surgery
  • Common Bile Duct Neoplasms / pathology*
  • Common Bile Duct Neoplasms / surgery
  • Female
  • Humans
  • Lymph Node Excision
  • Mastectomy
  • Middle Aged
  • Neoplasms, Multiple Primary / pathology*
  • Pancreaticoduodenectomy
  • Urinary Bladder Neoplasms / pathology*
  • Urinary Bladder Neoplasms / surgery