Psoriasin (S100A7): A Putative Urinary Marker for the Follow-Up of Patients With Bladder Squamous Cell Carcinomas

Electrophoresis. 1999 Feb;20(2):349-54. doi: 10.1002/(SICI)1522-2683(19990201)20:2<349::AID-ELPS349>3.0.CO;2-B.

Abstract

To search for bladder squamous cell carcinoma markers that are released to the urine a blind and systematic analysis of the protein profiles of fresh tumors, their secreted proteins, as well as the patient's urine was carried out using state-of-the-art proteomic technology. We review the data concerning the putative marker psoriasin (S100A7), which, alone or in combination with other biomarkers, may be valuable for the noninvasive follow-up of patients bearing these tumors.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Biomarkers, Tumor / biosynthesis
  • Biomarkers, Tumor / urine*
  • Calcium-Binding Proteins / biosynthesis
  • Calcium-Binding Proteins / urine*
  • Follow-Up Studies
  • Humans
  • Neoplasms, Squamous Cell / urine*
  • S100 Calcium Binding Protein A7
  • S100 Proteins
  • Urinary Bladder Neoplasms / urine*

Substances

  • Biomarkers, Tumor
  • Calcium-Binding Proteins
  • S100 Calcium Binding Protein A7
  • S100 Proteins
  • S100A7 protein, human