[Effects of active behavior in the postresuscitation period on the functional and morphological characteristics of the brain]

Anesteziol Reanimatol. 1999 Jan-Feb;(1):37-40.
[Article in Russian]

Abstract

Efficacy of prolonged (days 10-60 after resuscitation) regular activation of behavior by labyrinth training of 4-staged food search conditioned reflex is studied in rats subjected to 15-min circulation arrest. This training affected the function of the central nervous system, which manifested by decreased anxiety and a higher activity in the open field test. This functional exercise prevented fall-out of neurons in the fifth layer of hemispheres, of cerebellar Purkinje's cells, and of pyramidal neurons in hippocampal sector CA1. These results support the hypothesis proposed by A. M. Gurvich on the possibility of regulating the postresuscitation recovery of the central nervous system by neurophysiological treatment of the brain.

Publication types

  • Comparative Study
  • English Abstract

MeSH terms

  • Animals
  • Brain / anatomy & histology*
  • Brain / physiology*
  • Cardiopulmonary Resuscitation*
  • Cholesterol / blood
  • Data Interpretation, Statistical
  • Male
  • Motor Activity* / physiology
  • Neurons / physiology
  • Rats
  • Time Factors

Substances

  • Cholesterol