Combined phacoemulsification and goniosynechialysis for uncontrolled chronic angle-closure glaucoma after acute angle-closure glaucoma

Ophthalmology. 1999 Apr;106(4):669-74; discussion 674-5. doi: 10.1016/S0161-6420(99)90149-5.


Objective: To evaluate combined phacoemulsification, posterior chamber intraocular lens (PCIOL) implantation, and goniosynechialysis (phaco-GSL) prospectively in eyes with more than 180 degrees of peripheral anterior synechiae (PAS) and uncontrolled intraocular pressure (IOP) when performed within 6 months of an attack of acute angle-closure glaucoma (ACG).

Design: Prospective, noncontrolled clinical trial.

Participants: Patients who had presented with acute ACG and had persistently uncontrolled IOP despite successful laser iridotomy for pupillary block and argon laser peripheral iridoplasty for continued appositional closure after iridotomy.

Intervention: After the completion of phacoemulsification and posterior chamber lens implantation, goniosynechialysis was performed in 52 eyes of 48 patients.

Main outcome measures: Postoperative visual acuity, IOP, extent of PAS, and number of medications, if any, required for IOP control.

Results: Intraocular pressure was less than 20 mmHg in 47 eyes (90.4%) without medications; 4 were controlled with medications and 1 required filtration. Mean extent of PAS was reduced from 310 degrees to 60 degrees. Peripheral anterior synechiae formation or IOP elevation did not recur after 3 months after surgery up to 6 years. Eight patients achieved 20/20 visual acuity, while 44 patients had less than 20/20 visual acuity. No patient had worse visual acuity after surgery compared to before surgery.

Conclusion: Phaco-GSL and PCIOL implantation is effective in reducing PAS and IOP and improving visual acuity in eyes with persistent chronic ACG when performed within 6 months after treatment for acute ACG.

Publication types

  • Clinical Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acute Disease
  • Adult
  • Aged
  • Aged, 80 and over
  • Anterior Chamber / surgery
  • Chronic Disease
  • Female
  • Glaucoma, Angle-Closure / complications
  • Glaucoma, Angle-Closure / etiology
  • Glaucoma, Angle-Closure / surgery*
  • Gonioscopy*
  • Humans
  • Intraocular Pressure
  • Intraoperative Complications
  • Iris Diseases / surgery*
  • Lens Implantation, Intraocular
  • Male
  • Middle Aged
  • Phacoemulsification*
  • Postoperative Complications
  • Prospective Studies
  • Tissue Adhesions / surgery
  • Visual Acuity