Exact 95% confidence intervals for differences in binomial proportions

Comput Biol Med. 1999 Jan;29(1):83-7. doi: 10.1016/s0010-4825(98)00047-x.

Abstract

A method is described that allows exact 95% confidence intervals to be computed for differences in binomial proportions. The method itself is not iterative, but it uses the iteratively computed 95% confidence intervals for the individual binomial proportions. The method converges with the usual normal approximation method, as denominators become large. It correlates very closely with the Yates-corrected chi-square test. The method works regardless of the definition of success or failure in the proportions and regardless of the order of the proportions.

MeSH terms

  • Algorithms
  • Chi-Square Distribution
  • Computer Simulation*
  • Confidence Intervals*
  • Humans
  • Models, Statistical*