Propofol-induced pancreatitis: recurrence of pancreatitis after rechallenge

Chest. 1999 Apr;115(4):1198-9. doi: 10.1378/chest.115.4.1198.


We report a case of pancreatitis, which occurred while the patient was on a propofol drip and then recurred after resolution following an inadvertent rechallenge with propofol. The initial episode was associated with hypertriglyceridemia, whereas the latter was not. The association between propofol and pancreatitis is definite and may occur independently of significant hypertriglyceridemia.

Publication types

  • Case Reports

MeSH terms

  • Female
  • Humans
  • Hypertriglyceridemia / chemically induced
  • Hypnotics and Sedatives / adverse effects*
  • Middle Aged
  • Pancreatitis / chemically induced*
  • Propofol / adverse effects*
  • Recurrence
  • Respiration, Artificial


  • Hypnotics and Sedatives
  • Propofol