HIV: The deadly passenger in dendritic cells

Curr Biol. 1999 Apr 8;9(7):R248-50. doi: 10.1016/s0960-9822(99)80155-9.


A picture is emerging of how HIV subverts a normal immunological surveillance mechanism to establish primary infection. This involves the infection of dendritic cells at mucosal surfaces: as these cells then mature, they transport the virus to lymphoid tissue, where viral replication begins and infection of CD4(+) T cells occurs.

Publication types

  • Review

MeSH terms

  • Dendritic Cells / virology
  • HIV Infections / transmission
  • HIV Infections / virology*
  • HIV*
  • Humans