Ciliary body melanocytoma with anterior segment pigment dispersion and elevated intraocular pressure

J Glaucoma. 1999 Apr;8(2):129-33.


Purpose: To discuss a case in which melanocytoma of the ciliary body presented with widespread pigment dispersion and elevated intraocular pressure (IOP).

Methods: A 64-year old woman presented with increased IOP and persistent anterior segment inflammation in her right eye. She had undergone a trabeculectomy for uncontrolled IOP before presentation. Slit-lamp examination, gonioscopy, and ultrasound biomicroscopy revealed a ciliary body mass with extension into the subconjunctiva in addition to widespread pigmentary dispersion in the anterior segment. Enucleation of the right eye was performed for histopathologic evaluation, as a diagnosis of ciliary body melanoma was made on clinical examination.

Results: Histopathologic findings were diagnostic of a melanocytoma of the ciliary body with necrosis and focal malignant transformation with extension of melanocytoma cells and melanophages into the subconjunctival space, trabecular meshwork, and anterior chamber angle.

Conclusion: Melanocytoma of the ciliary body is a rare intraocular tumor that may present with pigment dispersion and secondary elevated IOP. Careful examination of the anterior segment is imperative in such cases.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Anterior Eye Segment / pathology*
  • Ciliary Body / pathology*
  • Exfoliation Syndrome / etiology*
  • Exfoliation Syndrome / pathology
  • Eye Enucleation
  • Female
  • Follow-Up Studies
  • Glaucoma, Open-Angle / etiology
  • Glaucoma, Open-Angle / pathology
  • Humans
  • Intraocular Pressure*
  • Middle Aged
  • Nevus, Pigmented / complications
  • Nevus, Pigmented / pathology*
  • Nevus, Pigmented / surgery
  • Ocular Hypertension / etiology*
  • Ocular Hypertension / pathology
  • Photomicrography
  • Uveal Neoplasms / complications
  • Uveal Neoplasms / pathology*
  • Uveal Neoplasms / surgery