Different effects of bisoprolol on heart rate in patients with ischemic or idiopathic dilated cardiomyopathy (a 24-hour Holter substudy of the Cardiac Insufficiency Bisoprolol Study [CIBIS])

R L Anthonio; J Brouwer; P Lechat; J Haaksma; L van der Ven; D J van Veldhuisen; H J Crijns; W H van Gilst

doi:10.1016/s0002-9149(99)00077-6

Different effects of bisoprolol on heart rate in patients with ischemic or idiopathic dilated cardiomyopathy (a 24-hour Holter substudy of the Cardiac Insufficiency Bisoprolol Study [CIBIS])

Am J Cardiol. 1999 Apr 15;83(8):1286-9, A10. doi: 10.1016/s0002-9149(99)00077-6.

Authors

R L Anthonio¹, J Brouwer, P Lechat, J Haaksma, L van der Ven, D J van Veldhuisen, H J Crijns, W H van Gilst

Affiliation

¹ Department of Clinical Pharmacology, University of Groningen, The Netherlands. R.L.Anthonio@thorax.azg.nl

PMID: 10215303
DOI: 10.1016/s0002-9149(99)00077-6

Abstract

The effect of beta blockade on heart rate in patients with either idiopathic or ischemic cardiomyopathy was studied. It was found that beta blockade reduced the early morning increase in heart rate to a greater extent in patients with idiopathic dilated cardiomyopathy than in those with ischemic dilated cardiomyopathy.

Publication types

Comparative Study
Research Support, Non-U.S. Gov't

MeSH terms

Adolescent
Adrenergic beta-Antagonists / therapeutic use*
Adult
Aged
Bisoprolol / therapeutic use*
Cardiomyopathy, Dilated / complications
Cardiomyopathy, Dilated / drug therapy
Cardiomyopathy, Dilated / physiopathology*
Circadian Rhythm
Electrocardiography, Ambulatory* / drug effects
Female
Follow-Up Studies
Heart Failure / drug therapy
Heart Failure / etiology
Heart Failure / physiopathology*
Heart Rate / drug effects*
Humans
Male
Middle Aged
Treatment Outcome

Substances

Adrenergic beta-Antagonists
Bisoprolol