Squamous cell carcinoma arising in a cutaneous epidermal cyst: case report and literature review

Am J Dermatopathol. 1999 Apr;21(2):174-7. doi: 10.1097/00000372-199904000-00012.


Although cutaneous epidermal (infundibular) cysts are extremely common lesions, neoplastic transformation of their epithelium is quite rare. We describe a patient with a squamous cell carcinoma arising in the wall of an otherwise conventional epidermal cyst. In addition, we review the literature concluding that most of the previously reported cases may not correspond to this rare occurrence.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adult
  • Aged
  • Carcinoma, Basal Cell / etiology*
  • Carcinoma, Basal Cell / pathology
  • Epidermal Cyst / complications*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Skin Diseases / complications*
  • Skin Neoplasms / etiology*
  • Skin Neoplasms / pathology