Emm Typing and Validation of Provisional M Types for Group A Streptococci

Emerg Infect Dis. Mar-Apr 1999;5(2):247-53. doi: 10.3201/eid0502.990209.

Abstract

This report discusses the following issues related to typing of group A streptococci (GAS): The development and use of the 5' emm variable region sequencing (emm typing) in relation to the existing serologic typing system; the designation of emm types in relation to M types; a system for validation of new emm types; criteria for validation of provisional M types to new M-types; a list of reference type cultures for each of the M-type or emm-type strains of GAS; the results of the first culture exchange program for a quality control testing system among the national and World Health Organization collaborating centers for streptococci; and dissemination of new approaches to typing of GAS to the international streptococcal community.

MeSH terms

  • Antigens, Bacterial*
  • Bacterial Outer Membrane Proteins*
  • Bacterial Proteins / genetics*
  • Bacterial Typing Techniques*
  • Carrier Proteins / genetics*
  • Laboratories
  • Streptococcus pyogenes / classification*

Substances

  • Antigens, Bacterial
  • Bacterial Outer Membrane Proteins
  • Bacterial Proteins
  • Carrier Proteins
  • streptococcal M protein