The parabrachial nucleus and conditioned taste aversion

Brain Res Bull. 1999 Feb;48(3):239-54. doi: 10.1016/s0361-9230(98)00173-7.


The parabrachial nucleus (PBN) surrounds the brachium conjunctivum in the dorsolateral pons. Although composed of numerous subnuclei, the PBN is typically organized into medial and lateral subdivisions according to their location relative to the brachium. In rodents, the medial PBN is part of the central gustatory system, whereas the lateral PBN is a component of the visceral sensory system. Lesions of the PBN disrupt conditioned taste aversion, a critically important learning mechanism that prevents the repeated ingestion of toxic food. Relevant neurobehavioral literature is reviewed to elucidate the role of the PBN in taste aversion learning.

Publication types

  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Animals
  • Avoidance Learning / physiology*
  • Discrimination Learning / physiology*
  • Pons / physiology*
  • Taste / physiology*