Selection of instruments in the core set for DC-ART, SMARD, physical therapy, and clinical record keeping in ankylosing spondylitis. Progress report of the ASAS Working Group. Assessments in Ankylosing Spondylitis

J Rheumatol. 1999 Apr;26(4):951-4.


To select specific instruments for each domain of the core set for endpoints in ankylosing spondylitis (AS), we gathered all instruments described in the literature to assess the domains chosen as endpoints in AS and sent them to 43 members of the Assessments in Ankylosing Spondylitis (ASAS) Working Group. The following domains were taken into account: function, pain, spinal mobility, patient global assessment, morning stiffness, peripheral joints and entheses, acute phase reactants, x-ray spine, x-ray hips, fatigue. For each instrument the members were asked to judge if the instrument was feasible and relevant. If an instrument was judged to be not feasible or not relevant by more than 50% of the respondents the instrument was deleted from the list. These data were presented during an ASAS workshop and the final decisions were about which instruments to include in the core set. This process was repeated separately for the settings disease controlling antirheumatic therapy (DC-ART), symptom modifying antirheumatic drugs (SMARD) and physical therapy, and clinical record keeping. The response rate to the questionnaire was 72%. For each domain one or more instruments were selected, except for Entheses and Fatigue. The chosen instruments were similar for the 3 above settings. Core sets of specific instruments were selected for the OMERACT filter test for relevance and feasibility. For all these instruments the remaining aspects of the OMERACT filter (truth and discrimination) should be assessed by literature review and if needed by additional research. It is recommended to use these instruments in all research projects in AS.

Publication types

  • Consensus Development Conference
  • Review

MeSH terms

  • Antirheumatic Agents / therapeutic use*
  • Evaluation Studies as Topic
  • Forms and Records Control / methods
  • Humans
  • Medical Records*
  • Outcome Assessment, Health Care / methods*
  • Physical Therapy Modalities*
  • Reproducibility of Results
  • Rheumatology / instrumentation*
  • Rheumatology / methods
  • Spondylitis, Ankylosing* / pathology
  • Spondylitis, Ankylosing* / physiopathology
  • Spondylitis, Ankylosing* / therapy
  • Surveys and Questionnaires


  • Antirheumatic Agents