[Kaposiform HHV-8 negative acroangiodermatitis in chronic venous insufficiency]

Hautarzt. 1999 Mar;50(3):208-13. doi: 10.1007/s001050050891.
[Article in German]

Abstract

A 76-year-old female patient developed severe manifestations of a kaposi-like acroangiodermatitis (so-called Mali's disease) due to chronic venous insufficiency of the lower extremities. The patient presented with large areas of confluent, violaceous or brown-black papules on both lower legs. Histologically, proliferation of thick-walled capillaries was seen in the upper dermis consisting of fully differentiated endothelial cells, as shown by immunohistochemistry. In contrast to true Kaposi's sarcoma, human-herpes-virus-8 DNA could not be detected by polymerase-chain-reaction in this condition. We review the diagnostic criteria used to distinguish between acroangiodermatitis, also called pseudo-Kaposi's sarcoma, and the true Kaposi's sarcoma.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Acrodermatitis / pathology*
  • Aged
  • Capillaries / pathology
  • Diagnosis, Differential
  • Female
  • Herpesvirus 8, Human* / isolation & purification
  • Humans
  • Sarcoma, Kaposi / pathology*
  • Skin / blood supply
  • Skin / pathology
  • Skin Neoplasms / pathology*
  • Vasculitis / pathology*
  • Venous Insufficiency / pathology*