A new B cell differentiation antigen (BDA) on normal and leukemic human B lymphocytes that is distinct from known DR (Ia-like) antigens

J Immunol. 1978 Dec;121(6):2322-8.

Abstract

A newly defined human B cell differentiation antigen, designated as BDA, has been defined and partially characterized. BDA is expressed on normal human B cells and lymphocytic leukemia cells at all stages of known differentiation (pre-B cells to plasma cells). It is distinct from DR (Ia-like) determinants and other known B cell surface constituents.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Antibody Specificity
  • Antigens*
  • B-Lymphocytes / immunology*
  • Binding Sites
  • Cattle
  • Complement C3
  • Fluorescent Antibody Technique
  • HLA Antigens
  • Haplorhini
  • Histocompatibility Antigens*
  • Humans
  • Immune Sera / pharmacology
  • Immunoglobulin Fc Fragments
  • Lymphoma, Large B-Cell, Diffuse / immunology*
  • Macaca mulatta
  • Rabbits
  • Receptors, Antigen, B-Cell

Substances

  • Antigens
  • Complement C3
  • HLA Antigens
  • Histocompatibility Antigens
  • Immune Sera
  • Immunoglobulin Fc Fragments
  • Receptors, Antigen, B-Cell