Abstract
Alcoholic extract of the leaves of Andrographis paniculata Ness (= AAP) was obtained by cold maceration. A dose of 300 mg/kg (1/6 of LD50) of the extract was selected to study hepatoprotective action against carbon tetrachloride-induced liver damage. The extract was found to be effective in preventing liver damage which was evident by morphological, biochemical and functional parameters.
MeSH terms
-
Animals
-
Carbon Tetrachloride Poisoning / pathology
-
Carbon Tetrachloride Poisoning / physiopathology
-
Carbon Tetrachloride Poisoning / prevention & control*
-
Chemical and Drug Induced Liver Injury / pathology
-
Chemical and Drug Induced Liver Injury / physiopathology
-
Chemical and Drug Induced Liver Injury / prevention & control*
-
Female
-
Liver / pathology
-
Liver Function Tests
-
Male
-
Plant Extracts / therapeutic use
-
Plants, Medicinal / chemistry*
-
Rats