Is hexokinase really a sugar sensor in plants?

Trends Plant Sci. 1999 Mar;4(3):117-120. doi: 10.1016/s1360-1385(99)01377-1.


The molecular mechanisms by which plant cells sense sugar levels are not understood, but current models (adapted from models for sugar sensing in yeast) favour hexokinase as the primary sugar sensor. However, the hypothesis that yeast hexokinase has a signalling function has not been supported by more recent studies and the idea that hexokinase is involved in sugar sensing in plants has yet to be proven.