Objective: To study the hypoglycemic effect of Jiangtangkang (JTK), a Chrysanthemum product and its influence on sensitivity of insulin in non-insulin dependant diabetes mellitus (NIDDM).
Methods: Newly discovered (71 cases) and poorly controlled (117 cases) NIDDM were divided to JTK, 8 g each time, 3 times per day, and the control (Glibenclazide in newly discovered, no treatment in poorly controlled) group respectively.
Results: After 2 months of treatment, the fasting blood glucose (FBG), postprandial blood glucose (PBG), glucosylated hemoglobin (GHb) improved remarkably and insulin of plasma remained unchanged in JTK group, their blood viscosity and triglyceride decreased after 6-month reatment, the FBG, PBG lowered in the control group while their viscosity and lipids were unaffected. Insulin tolerance test on newly discovered NIDDMs showed an increased sensitivity to insulin, their serum chromium elevated, and the urinary albumin in poorly controlled persons lowered significantly.
Conclusions: JTK might improve the sensitivity to insulin and decrease the blood viscosity in NIDDM.