Lemierre Syndrome and Acute Mastoiditis

Arch Otolaryngol Head Neck Surg. 1999 May;125(5):589-91. doi: 10.1001/archotol.125.5.589.


Lemierre syndrome seldom follows an episode of pharyngotonsillitis. Characteristically, it is comprised of septic thrombosis of the internal jugular vein and bacteremia, leading to lung emboli and metastatic abscess formation. We describe Lemierre syndrome that complicates an acute mastoiditis, with considerations regarding its pathogenesis and management. Despite its sporadic occurrence, awareness of Lemierre syndrome is important, since early recognition reduces both the morbidity and mortality associated with it.

Publication types

  • Case Reports

MeSH terms

  • Acute Disease
  • Adolescent
  • Fusobacterium Infections / complications*
  • Fusobacterium necrophorum*
  • Humans
  • Jugular Veins*
  • Male
  • Mastoiditis / complications*
  • Mastoiditis / microbiology
  • Sepsis / complications
  • Sinusitis / complications
  • Sinusitis / microbiology*
  • Syndrome
  • Thrombosis / complications*
  • Thrombosis / microbiology
  • Tonsillitis / complications