A multiple comparison procedure for three- and four-armed controlled clinical trials

Stat Med. 1999 Apr 15;18(7):787-98. doi: 10.1002/(sici)1097-0258(19990415)18:7<787::aid-sim77>3.0.co;2-m.


Multi-armed controlled trials are becoming increasingly popular. With them comes the issue of how to deal with the possibility of multiple Type I errors. This paper recommends a simple and appealing method for three- and four-armed trials in which one is a control. This article is a US Government work and is in the public domain in the United States.

MeSH terms

  • Controlled Clinical Trials as Topic / statistics & numerical data*
  • Humans
  • Hypertension / diet therapy*
  • Models, Statistical*