Induced endothelial cell loss in phacoemulsification using topical anesthesia plus intracameral lidocaine

J Cataract Refract Surg. 1999 May;25(5):640-2. doi: 10.1016/s0886-3350(99)00008-5.

Abstract

Purpose: To determine whether lidocaine 1% injected into the anterior chamber during phacoemulsification damaged the corneal endothelium.

Setting: Ophthalmology Service, University Hospital, San Juan de Alicante, Spain.

Methods: In 19 eyes of 19 patients, small incision phacoemulsification and foldable lens (AcrySof MA60BM) implantation was performed using topical anesthesia supplemented by lidocaine 1% (0.3 mL) in the anterior chamber. All cases were operated by the same surgeon. Specular microscopy was performed before surgery and 1 and 3 months postoperatively.

Results: Mean endothelial cell loss was 5.41% +/- 8.50 (SD) at 1 month and 5.93 +/- 8.50% at 3 months.

Conclusions: The endothelial damage was similar to that described by other authors, suggesting that phacoemulsification surgery can be performed successfully using topical anesthesia supplemented by lidocaine 1% in the anterior chamber.

Publication types

  • Comparative Study

MeSH terms

  • Aged
  • Anesthesia, Local / adverse effects*
  • Anesthetics, Local / administration & dosage
  • Anesthetics, Local / adverse effects*
  • Cell Count
  • Corneal Diseases / chemically induced*
  • Corneal Diseases / diagnostic imaging
  • Corneal Diseases / pathology
  • Endothelium, Corneal / diagnostic imaging
  • Endothelium, Corneal / drug effects*
  • Endothelium, Corneal / pathology
  • Follow-Up Studies
  • Humans
  • Injections
  • Lidocaine / administration & dosage
  • Lidocaine / adverse effects*
  • Ophthalmic Solutions
  • Phacoemulsification*
  • Ultrasonography

Substances

  • Anesthetics, Local
  • Ophthalmic Solutions
  • Lidocaine