A blinded, placebo-controlled study of the efficacy of borage seed oil and fish oil in the management of canine atopy

Vet Rec. 1999 Apr 10;144(15):405-7. doi: 10.1136/vr.144.15.405.

Abstract

Twenty-one dogs with atopy were entered into a blinded, placebo-controlled study lasting eight weeks. They were randomly divided into three groups and were all given supplementary oils orally once daily. The dogs in groups A and B were given borage seed oil and fish oil in combination (Viacutan; Boehringer Ingelheim Vetmedica) to provide 176 mg/kg or 88 mg/kg borage seed oil respectively. The dogs in group C were given 204 mg/kg olive oil as a placebo. They were all re-examined after four and eight weeks and scored for pruritus, erythema, oedema, alopecia and self-excoriation. After eight weeks the scores for erythema and self-excoriation, and the total score for the dogs in group A, and the total score for the dogs in group B were significantly reduced (P < 0.05). The dogs in group C showed no significant improvement.

Publication types

  • Clinical Trial
  • Randomized Controlled Trial

MeSH terms

  • Animals
  • Dermatitis, Atopic / pathology
  • Dermatitis, Atopic / therapy*
  • Dog Diseases / pathology
  • Dog Diseases / therapy*
  • Dogs
  • Double-Blind Method
  • Erythema
  • Fish Oils*
  • Plant Oils*
  • Treatment Outcome

Substances

  • Fish Oils
  • Plant Oils