Low levels of nucleotide diversity at homoeologous Adh loci in allotetraploid cotton (Gossypium L.)

Mol Biol Evol. 1999 Apr;16(4):491-501. doi: 10.1093/oxfordjournals.molbev.a026131.

Abstract

Levels of genetic diversity within and among populations and species are shaped by both external (population-level) and internal (genomic and genic) evolutionary forces. To address the effect of internal pressures, we estimated nucleotide diversity for a pair of homoeologous Adh loci in an allotetraploid species, Gossypium hirsutum. These data represent the first such estimates for a pair of homoeologous nuclear loci in plants. Estimates of nucleotide diversity for AdhA in Gossypium are lower than those for any plant nuclear gene yet described. This low diversity appears to reflect primarily a history of repeated, severe genetic bottlenecks associated with both speciation and recent domestication, supplemented by an unusually slow nucleotide substitution rate and an autogamous breeding system. While not statistically supportable, the sum of the observations also suggest differential evolutionary dynamics at each of the homoeologous loci.

Publication types

  • Comparative Study
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Alcohol Dehydrogenase / genetics*
  • Base Sequence
  • DNA Primers / genetics
  • DNA, Plant / genetics
  • Evolution, Molecular
  • Genetic Variation
  • Gossypium / enzymology*
  • Gossypium / genetics*
  • Models, Genetic
  • Molecular Sequence Data
  • Mutation
  • Phylogeny
  • Polymorphism, Genetic
  • Polyploidy
  • Recombination, Genetic
  • Sequence Homology, Nucleic Acid

Substances

  • DNA Primers
  • DNA, Plant
  • Alcohol Dehydrogenase

Associated data

  • GENBANK/AF085064
  • GENBANK/AF085065
  • GENBANK/AF085066
  • GENBANK/AF085067
  • GENBANK/AF085068
  • GENBANK/AF085069
  • GENBANK/AF085070
  • GENBANK/AF085071
  • GENBANK/AF085072
  • GENBANK/AF085073
  • GENBANK/AF085074
  • GENBANK/AF085075
  • GENBANK/AF085076
  • GENBANK/AF085077
  • GENBANK/AF085078
  • GENBANK/AF085079
  • GENBANK/AF085080
  • GENBANK/AF085081
  • GENBANK/AF085082
  • GENBANK/AF085083
  • GENBANK/AF085084
  • GENBANK/AF085085
  • GENBANK/AF085812
  • GENBANK/AF085813
  • GENBANK/AF085814
  • GENBANK/AF085815
  • GENBANK/AF085816
  • GENBANK/AF085817
  • GENBANK/AF085818
  • GENBANK/AF085819