Pulmonary Langerhans' cell histiocytosis: radiologic resolution following smoking cessation

Chest. 1999 May;115(5):1452-5. doi: 10.1378/chest.115.5.1452.


We describe two patients with histologically proven pulmonary Langerhans' cell histiocytosis in whom radiologic improvement occurred following smoking cessation. The patients had 23- and 25-pack-year smoking histories, respectively. High-resolution CT revealed multiple small nodules, located predominantly in the upper and middle lung fields. There was a close temporal relationship between smoking cessation and radiologic improvement.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Female
  • Histiocytosis, Langerhans-Cell / diagnostic imaging*
  • Histiocytosis, Langerhans-Cell / pathology
  • Humans
  • Lung / diagnostic imaging*
  • Lung / pathology
  • Lung Diseases / diagnostic imaging
  • Lung Diseases / pathology
  • Middle Aged
  • Smoking Cessation*
  • Tomography, X-Ray Computed