Fatal case due to methicillin-resistant Staphylococcus aureus small colony variants in an AIDS patient

Emerg Infect Dis. May-Jun 1999;5(3):450-3. doi: 10.3201/eid0503.990319.

Abstract

We describe the first known case of a fatal infection with small colony variants of methicillin-resistant Staphylococcus aureus in a patient with AIDS. Recovered from three blood cultures as well as from a deep hip abscess, these variants may have resulted from long-term antimicrobial therapy with trimethoprim/sulfamethoxazole for prophylaxis of Pneumocystis carinii pneumonia.

Publication types

  • Case Reports

MeSH terms

  • AIDS-Related Opportunistic Infections / drug therapy*
  • AIDS-Related Opportunistic Infections / microbiology
  • Abscess / drug therapy
  • Abscess / microbiology
  • Adult
  • Bacteremia / drug therapy
  • Bacteremia / microbiology
  • Fatal Outcome
  • Hip
  • Humans
  • Male
  • Methicillin Resistance*
  • Osteomyelitis / drug therapy
  • Osteomyelitis / microbiology
  • Polymorphism, Genetic
  • Staphylococcal Infections / drug therapy*
  • Staphylococcal Infections / microbiology
  • Staphylococcus aureus / drug effects*
  • Staphylococcus aureus / genetics*
  • Staphylococcus aureus / growth & development