Thin-layer cytology meets viral hybrid capture

Adv Anat Pathol. 1999 May;6(3):161-4. doi: 10.1097/00125480-199905000-00005.


This commentary addresses the benefits of liquid-based thin-layer cervical cytology, and the applicability of residual samples for human papilloma virus assay. The potential for use of this technology in wide-scale screening as well as the many unanswered issues, in particular cost-benefit ratio and financing, are also discussed.

MeSH terms

  • Carcinoma, Squamous Cell / pathology*
  • Cervical Intraepithelial Neoplasia / pathology*
  • Female
  • Histocytological Preparation Techniques*
  • Humans
  • Papillomaviridae / isolation & purification*
  • Predictive Value of Tests
  • Sensitivity and Specificity
  • Uterine Cervical Neoplasms / pathology*
  • Vaginal Smears / economics
  • Vaginal Smears / methods*
  • Vaginal Smears / trends