Epidemiology and outcome of HIV infection in North-East Scotland (1985-1997)

J Infect. 1999 Mar;38(2):107-10. doi: 10.1016/s0163-4453(99)90077-4.


Objective: to assess the epidemiology of HIV infection in North-East Scotland.

Methods: retrospective casenote review of all HIV-infected patients who have had contact with the Infection Unit in Aberdeen.

Results: one hundred and forty-two HIV-infected patients were treated between April 1985 and December 1997. The risk behaviour related to the acquisition of the HIV infection was: 56 (39%) homosexually infected, 45 (32%) heterosexually-infected, 34 (24%) injecting drug users (IDUs), and seven (5%) blood products or not known. Sixteen of the 45 (36%) heterosexually-infected patients were native to Africa and 16 of the 34 (31%) IDUs were prisoners in Peterhead prison at the time of referral. Fifty-two (37%) of the cohort continue to attend the Infection Unit, 41 (29%) have relocated, 40 (28%) have died and nine (6%) have been lost to follow-up. The ratio of heterosexual:homosexual men:IDUs changed significantly between the first 7 years (12:21:25) and the second 6 years (33:35:9) of the review, with significantly more patients being infected through heterosexual contact and fewer infected by IDU in the second period-P<0.001. The median AIDS survival was 17 months. Survival was significantly longer in those patients who took anti-retroviral therapy (median = 20 months) than in the patients who opted not to take anti-retroviral therapy (median = 11 months)-P<0.01.

Conclusions: Although homosexual contact represents the commonest risk group for HIV infection in this region, the number of heterosexually-infected patients has increased significantly in the last 5 years. Temporary residents account for one-third of the HIV-infected population cared for in NE Scotland. Almost half of those lost to follow-up have returned to Africa or been released from prison. The introduction of anti-retroviral therapy has resulted in a dramatic improvement in AIDS survival in our cohort as it has done elsewhere.

MeSH terms

  • Africa
  • Anti-HIV Agents / therapeutic use
  • Cohort Studies
  • Female
  • HIV Infections / drug therapy
  • HIV Infections / epidemiology*
  • HIV Infections / etiology
  • Hemophilia A / complications
  • Heterosexuality
  • Homosexuality
  • Humans
  • Male
  • Prisoners
  • Retrospective Studies
  • Risk Factors
  • Scotland / epidemiology
  • Substance Abuse, Intravenous / complications
  • Survival Rate
  • Treatment Outcome


  • Anti-HIV Agents