Abstract
We report a 49-year-old woman with Creutzfeldt-Jakob disease (CJD). In addition to typical high-signal lesions on proton-density and T2-weighted images there was high signal in the globus pallidus bilaterally on T1-weighted images. The latter feature has not been described previously and probably due to deposition of prion protein, as found at autopsy.
MeSH terms
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Caudate Nucleus / pathology
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Contrast Media
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Creutzfeldt-Jakob Syndrome / diagnosis
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Creutzfeldt-Jakob Syndrome / pathology*
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Fatal Outcome
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Female
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Gadolinium DTPA
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Globus Pallidus / pathology*
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Gyrus Cinguli / pathology
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Humans
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Image Processing, Computer-Assisted / methods
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Immunohistochemistry
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Magnetic Resonance Imaging / methods*
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Middle Aged
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Prions / analysis
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Putamen / pathology
Substances
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Contrast Media
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Prions
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Gadolinium DTPA