Four-week supplementation with a natural dietary compound produces favorable changes in body composition

Adv Ther. Sep-Oct 1998;15(5):305-14.

Abstract

The purpose of this study was to determine whether a natural dietary supplement produced favorable changes in body composition during a 4-week diet- and-exercise program. The active compound contains a patented combination of chromium picolinate, inulin, capsicum, L-phenylalanine, and other lipotropic nutrients. A double-blind, weight-loss intervention design was used. Participants were randomly assigned to either a diet/exercise/supplement group (n = 56) or a diet/exercise/placebo group (n = 67). Caloric intake was reduced to 1500 kcal/d and participants walked for 45 minutes, 5 days a week, to attain between 60% and 80% of predicted maximal heart rate. Analysis of covariance (ANCOVA) showed significant differences (P < .05) between groups in percent body fat, fat mass, and fat-free mass; no significant differences were found (P > .05) in body weight, body mass index, or energy intake. Independent t tests showed no significant differences (P > .05) in diet composition between groups. Results indicate that the addition of a natural dietary supplement during a 4-week diet-and-exercise weight-loss program accelerates the rate of body fat loss and helps maintain fat-free mass (lean tissue), thereby producing favorable changes in body composition.

Publication types

  • Clinical Trial
  • Comparative Study
  • Randomized Controlled Trial

MeSH terms

  • Adipose Tissue / metabolism
  • Adult
  • Analysis of Variance
  • Body Composition*
  • Body Mass Index
  • Capsicum
  • Choline / therapeutic use*
  • Dietary Supplements*
  • Double-Blind Method
  • Energy Metabolism
  • Female
  • Humans
  • Inulin / administration & dosage
  • Inulin / therapeutic use*
  • Iron Chelating Agents / administration & dosage
  • Male
  • Middle Aged
  • Obesity / diet therapy*
  • Obesity / metabolism
  • Obesity / therapy
  • Phenylalanine / administration & dosage
  • Picolinic Acids / administration & dosage
  • Picolinic Acids / therapeutic use*
  • Plants, Medicinal
  • Reference Values
  • Skinfold Thickness
  • Treatment Outcome
  • Vanadium Compounds / therapeutic use*

Substances

  • Biotrol
  • Iron Chelating Agents
  • Picolinic Acids
  • Vanadium Compounds
  • Phenylalanine
  • Inulin
  • Choline
  • picolinic acid