Development of Dickie's small eye, a mutation in the house mouse

Anat Embryol (Berl). 1978 Dec 5;155(1):81-6. doi: 10.1007/BF00315732.


A new semidominant mutation in the laboratory mouse, Dickie's small eye (Dey), is described. It is localized on chromosome 2. Heterozygotes show reduced body size, small eyes with coloboma, small or lacking lens with cataract, abnormal folding of the retina and reduction of the pigment layer. The anterior chamber is usually missing. Homozygotes apparently die early in pregnancy.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Cataract / genetics
  • Coloboma / genetics
  • Eye Abnormalities / genetics*
  • Heterozygote
  • Homozygote
  • Mice
  • Mice, Mutant Strains*
  • Retina / abnormalities