PKS1, a substrate phosphorylated by phytochrome that modulates light signaling in Arabidopsis

Science. 1999 May 28;284(5419):1539-41. doi: 10.1126/science.284.5419.1539.

Abstract

Plants constantly monitor their light environment in order to grow and develop optimally, in part through use of the phytochromes, which sense red/far-red light. A phytochrome binding protein, PKS1 (phytochrome kinase substrate 1), was identified that is a substrate for light-regulated phytochrome kinase activity in vitro. In vivo experiments suggest that PKS1 is phosphorylated in a phytochrome-dependent manner and negatively regulates phytochrome signaling. The data suggest that phytochromes signal by serine-threonine phosphorylation.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Amino Acid Sequence
  • Arabidopsis / genetics
  • Arabidopsis / metabolism*
  • Arabidopsis Proteins*
  • Carrier Proteins / chemistry
  • Carrier Proteins / genetics
  • Carrier Proteins / metabolism*
  • Genes, Plant
  • Histidine Kinase
  • Intracellular Signaling Peptides and Proteins*
  • Light*
  • Membrane Proteins
  • Molecular Sequence Data
  • Mutation
  • Phosphoproteins / chemistry
  • Phosphoproteins / genetics
  • Phosphoproteins / metabolism*
  • Phosphorylation
  • Photoreceptor Cells*
  • Phytochrome / metabolism*
  • Phytochrome A
  • Phytochrome B
  • Plant Proteins*
  • Protein Kinases / metabolism
  • Protein-Serine-Threonine Kinases / metabolism
  • Recombinant Fusion Proteins / metabolism
  • Signal Transduction*
  • Transcription Factors*

Substances

  • Arabidopsis Proteins
  • Carrier Proteins
  • Intracellular Signaling Peptides and Proteins
  • Membrane Proteins
  • PHYA protein, Arabidopsis
  • PHYB protein, Arabidopsis
  • PKS1 protein, Arabidopsis
  • PKS1 protein, plant
  • Phosphoproteins
  • Phytochrome A
  • Plant Proteins
  • Recombinant Fusion Proteins
  • Transcription Factors
  • Phytochrome
  • Phytochrome B
  • Protein Kinases
  • Protein-Serine-Threonine Kinases
  • Histidine Kinase

Associated data

  • GENBANK/AF149053