Current therapy of cutaneous melanoma

Cutis. 1999 May;63(5):293-8.


We review the current therapy for cutaneous malignant melanoma. Early surgical resection offers the best likelihood of cure. The initial staging of melanoma patients determines subsequent therapeutic decisions and follow-up care. The prognosis and appropriate therapy for each stage of melanoma are discussed. We review the controversy over lymph node dissection, and recent recommendations for the use of lymphoscintigraphy. Interferon-alpha continues to be the only Food and Drug Administration-approved adjuvant therapy for high-risk patients. In addition, the follow-up care of melanoma patients will be discussed.

Publication types

  • Review

MeSH terms

  • Antineoplastic Agents / therapeutic use*
  • Chemotherapy, Adjuvant
  • Humans
  • Interferon-alpha / therapeutic use*
  • Melanoma / drug therapy*
  • Melanoma / pathology
  • Melanoma / surgery*
  • Neoplasm Staging
  • Prognosis
  • Skin Neoplasms / drug therapy*
  • Skin Neoplasms / pathology
  • Skin Neoplasms / surgery*


  • Antineoplastic Agents
  • Interferon-alpha