Pain affect without pain sensation in a patient with a postcentral lesion

Pain. 1999 May;81(1-2):211-4. doi: 10.1016/s0304-3959(99)00012-3.


We report findings from clinical examination and cutaneous laser stimulation in a 57-year-old male, who suffered from a right-sided postcentral stroke. In this patient, we were able to demonstrate (i) a dissociation of discriminative and affective components of pain perception and, for the first time in humans, (ii) the dependence of sensory-discriminative pain component and first pain sensation on the integrity of the lateral pain system.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Affect / physiology*
  • Brain Ischemia / diagnosis
  • Brain Ischemia / physiopathology*
  • Cerebrovascular Disorders / diagnosis
  • Cerebrovascular Disorders / physiopathology
  • Hot Temperature
  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Middle Aged
  • Pain / physiopathology*
  • Pain / psychology*
  • Pain Threshold / physiology
  • Physical Stimulation
  • Sensation / physiology*
  • Somatosensory Cortex / blood supply*