Early steps in pituitary organogenesis

Trends Genet. 1999 Jun;15(6):236-40. doi: 10.1016/s0168-9525(99)01742-4.


Significant advances have been made in defining the transcription cascade that is responsible for the early steps of pituitary formation and the environmental signals that induce, pattern and specify the pituitary gland and its cell types. It is now possible to outline the molecular mechanisms underlying the formation of the pituitary gland, as well as the initial development of organ-specific cell types.

Publication types

  • Review

MeSH terms

  • Animals
  • Embryonic and Fetal Development / genetics*
  • Humans
  • Models, Biological
  • Morphogenesis
  • Pituitary Gland / embryology*
  • Transcription, Genetic*